Disease: Developmental regression
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZBTB20 Q9HC78 zinc finger and BTB domain containing 20 0.97 0.566 0.731
VPS13A Q96RL7 vacuolar protein sorting 13 homolog A 9.3E-22 0.650 0.577
UBAC2 Q8NBM4 UBA domain containing 2 6.3E-03 0.638 0.654
TYROBP O43914 transmembrane immune signaling adaptor TYROBP 0.20 0.573 0.769
TUBB4A P04350 tubulin beta 4A class IVa Cellular structure 0.11 0.608 0.615
TTPA P49638 alpha tocopherol transfer protein Transporter 1.4E-03 0.612 0.577
TRNK tRNA 0.608 0.577
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
TANGO2 Q6ICL3 transport and golgi organization 2 homolog 1.5E-04 0.666 0.615
STAT4 Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 0.77 0.471 0.769
SLC39A14 Q15043 solute carrier family 39 member 14 Transporter 0.15 0.653 0.615
SEMA4A Q9H3S1 semaphorin 4A Signaling 1.8E-05 0.569 0.692
RPS20 P60866 ribosomal protein S20 Nucleic acid binding 2.1E-02 0.610 0.692
RANBP2 P49792 RAN binding protein 2 Enzyme modulator 1.00 0.578 0.615
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
PMS1 P54277 PMS1 homolog 1, mismatch repair system component Nucleic acid binding 1.3E-17 0.569 0.654
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIGY Q3MUY2 phosphatidylinositol glycan anchor biosynthesis class Y 9.7E-02 0.628 0.577
PEX6 Q13608 peroxisomal biogenesis factor 6 6.3E-06 0.547 0.731
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
NDUFAF6 Q330K2 NADH:ubiquinone oxidoreductase complex assembly factor 6 9.1E-08 0.659 0.615
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731